activity
20142018
most citedNonlinear drift-diffusion model of gating in the fast Cl channel

7 citations · 19 across the 7 of their papers we have counts for

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5 papers · 1 filter

physics.bio-ph2018★ 2 cited

Reduction of a kinetic model for Na+ channel activation, and fast and slow inactivation within a neural or cardiac membrane

S. R. Vaccaro

A fifteen state kinetic model for Na+ channel gating that describes the coupling between three activation sensors, a two-stage fast inactivation process and slow inactivated states…

physics.bio-ph2017

Rate equations for a Na+ channel gating master equation during the action potential within a neural membrane

S. R. Vaccaro

The action potential in a neural membrane is generated by Na+ and K+ channel ionic currents that may be calculated from a current equation and the rate equations for activation var…

physics.bio-ph2016★ 1 cited

Derivation of Hodgkin-Huxley equations for a Na+ channel from a master equation for coupled activation and inactivation

S. R. Vaccaro

The Na+ current in nerve and muscle membranes may be described in terms of the activation variable m(t) and the inactivation variable h(t), which are dependent on the transitions o…

physics.bio-ph2015

Voltage dependence of rate functions for Na+ channel inactivation within a membrane

Samuel R Vaccaro

The inactivation of a Na+ channel occurs when the activation of the charged S4 segment of domain DIV is followed by the binding of an intracellular hydrophobic motif which blocks c…

physics.bio-ph2014★ 2 cited

Voltage dependence of Hodgkin-Huxley rate functions for a multi-stage K channel voltage sensor within a membrane

Samuel R. Vaccaro

The activation of a channel sensor in two sequential stages during a voltage clamp may be described as the translocation of a Brownian particle in an energy landscape with tw…