7 citations · 19 across the 7 of their papers we have counts for
7 papers
Reduction of a kinetic model for Na+ channel activation, and fast and slow inactivation within a neural or cardiac membrane
S. R. Vaccaro
A fifteen state kinetic model for Na+ channel gating that describes the coupling between three activation sensors, a two-stage fast inactivation process and slow inactivated states…
Rate equations for a Na+ channel gating master equation during the action potential within a neural membrane
S. R. Vaccaro
The action potential in a neural membrane is generated by Na+ and K+ channel ionic currents that may be calculated from a current equation and the rate equations for activation var…
Derivation of Hodgkin-Huxley equations for a Na+ channel from a master equation for coupled activation and inactivation
S. R. Vaccaro
The Na+ current in nerve and muscle membranes may be described in terms of the activation variable m(t) and the inactivation variable h(t), which are dependent on the transitions o…
Voltage dependence of rate functions for Na+ channel inactivation within a membrane
Samuel R Vaccaro
The inactivation of a Na+ channel occurs when the activation of the charged S4 segment of domain DIV is followed by the binding of an intracellular hydrophobic motif which blocks c…
Nonlinear drift-diffusion model of gating in the fast Cl channel
Samuel R. Vaccaro
The dynamics of the open or closed state region of an ion channel may be described by a probability density which satisfies a Fokker-Planck equation. The closed state dwel…
Voltage dependence of Hodgkin-Huxley rate functions for a multi-stage K channel voltage sensor within a membrane
Samuel R. Vaccaro
The activation of a channel sensor in two sequential stages during a voltage clamp may be described as the translocation of a Brownian particle in an energy landscape with tw…
Position-dependent stochastic diffusion model of ion channel gating
Samuel Robert Vaccaro
A position-dependent stochastic diffusion model of gating in ion channels is developed by considering the spatial variation of the diffusion coefficient between the closed and open…