381 citations · 1k across the 13 of their papers we have counts for
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Biological Insights from Integrative Modeling of Intrinsically Disordered Protein Systems
Zi Hao Liu, Maria Tsanai, Oufan Zhang +2
Intrinsically disordered proteins and regions are increasingly appreciated for their abundance in the proteome and the many functional roles they play in the cell. In this short re…
Computational Methods to Investigate Intrinsically Disordered Proteins and their Complexes
Zi Hao Liu, Maria Tsanai, Oufan Zhang +2
In 1999 Wright and Dyson highlighted the fact that large sections of the proteome of all organisms are comprised of protein sequences that lack globular folded structures under phy…
A Curated Rotamer Library for Common Post-Translational Modifications of Proteins
Oufan Zhang, Shubhankar A. Naik, Zi Hao Liu +2
Sidechain rotamer libraries of the common amino acids of a protein are useful for folded protein structure determination and for generating ensembles of intrinsically disordered pr…
Learning to Evolve Structural Ensembles of Unfolded and Disordered Proteins Using Experimental Solution Data
Oufan Zhang, Mojtaba Haghighatlari, Jie Li +5
We have developed a Generative Recurrent Neural Networks (GRNN) that learns the probability of the next residue torsions from the pre…
Learning Correlations between Internal Coordinates to improve 3D Cartesian Coordinates for Proteins
Jie Li, Oufan Zhang, Seokyoung Lee +5
We consider a generic representation problem of internal coordinates (bond lengths, valence angles, and dihedral angles) and their transformation to 3-dimensional Cartesian coordin…
Extended Experimental Inferential Structure Determination Method for Evaluating the Structural Ensembles of Disordered Protein States
James Lincoff, Mickael Krzeminski, Mojtaba Haghighatlari +5
Characterization of proteins with intrinsic or unfolded state disorder comprises a new frontier in structural biology, requiring the characterization of diverse and dynamic structu…