137 citations · 142 across the 5 of their papers we have counts for
7 papers
Computational Methods to Investigate Intrinsically Disordered Proteins and their Complexes
Zi Hao Liu, Maria Tsanai, Oufan Zhang +2
In 1999 Wright and Dyson highlighted the fact that large sections of the proteome of all organisms are comprised of protein sequences that lack globular folded structures under phy…
A Curated Rotamer Library for Common Post-Translational Modifications of Proteins
Oufan Zhang, Shubhankar A. Naik, Zi Hao Liu +2
Sidechain rotamer libraries of the common amino acids of a protein are useful for folded protein structure determination and for generating ensembles of intrinsically disordered pr…
Learning Correlations between Internal Coordinates to improve 3D Cartesian Coordinates for Proteins
Jie Li, Oufan Zhang, Seokyoung Lee +5
We consider a generic representation problem of internal coordinates (bond lengths, valence angles, and dihedral angles) and their transformation to 3-dimensional Cartesian coordin…
Configurational Entropy of Folded Proteins and its Importance for Intrinsically Disordered Proteins
Meili Liu, Akshaya K. Das, James Lincoff +5
Many pairwise additive force fields are in active use for intrinsically disordered proteins (IDPs) and regions (IDRs), some of which modify energetic terms to improve description o…
Comparative Roles of Charge, and Hydrophobic Interactions in Sequence-Dependent Phase Separation of Intrinsically Disordered Proteins
Suman Das, Yi-Hsuan Lin, Robert M. Vernon +2
Endeavoring toward a transferable, predictive coarse-grained explicit-chain model for biomolecular condensates underlain by liquid-liquid phase separation (LLPS), we conducted mult…
Extended Experimental Inferential Structure Determination Method for Evaluating the Structural Ensembles of Disordered Protein States
James Lincoff, Mickael Krzeminski, Mojtaba Haghighatlari +5
Characterization of proteins with intrinsic or unfolded state disorder comprises a new frontier in structural biology, requiring the characterization of diverse and dynamic structu…