309 citations · 1.6k across the 65 of their papers we have counts for
3 papers · 1 filter
A nonequilibrium strategy for fast target search on the genome
F. Cagnetta, D. Michieletto, D. Marenduzzo
Vital biological processes such as genome repair require fast and efficient binding of selected proteins to specific target sites on DNA. Here we propose an active target search me…
Shaping Epigenetic Memory via Genomic Bookmarking
Davide Michieletto, Michael Chiang, Davide Coli +4
Reconciling the stability of epigenetic patterns with the rapid turnover of histone modifications and their adaptability to external stimuli is an outstanding challenge. Here, we p…
Chromosome-wide simulations uncover folding pathway and 3D organization of interphase chromosomes
Davide Michieletto, Davide Marenduzzo, Ajazul H. Wani
Three-dimensional interphase organization of metazoan genomes has been linked to cellular identity. However, the principles governing 3D interphase genome architecture and its fait…