402 citations · 8.7k across the 191 of their papers we have counts for
3 papers · 2 filters
Modelling transcriptional silencing and its coupling to 3D genome organisation
Massimiliano Semeraro, Giuseppe Negro, Davide Marenduzzo +1
Timely up- or down-regulation of gene expression is crucial for cellular differentiation and function. While gene upregulation via transcriptional activators has been extensively i…
Topological weight and structural diversity of polydisperse chromatin loop networks
Andrea Bonato, Enrico Carlon, Sergey Kitaev +2
Current biophysical models for transcriptionally active chromatin view this as a polymer with sticky sites, mimicking transcription units such as promoters and enhancers which inte…
Oscillation in the SIRS model
D. Marenduzzo, A. T. Brown, C. Miller +1
We study the SIRS epidemic model, both analytically and on a square lattice. The analytic model has two stable solutions, post outbreak/epidemic (no infected, ) and the endemi…