88 citations · 126 across the 9 of their papers we have counts for
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stat.ME2017★ 22 cited
Cancer phase I trial design using drug combinations when a fraction of dose limiting toxicities is attributable to one or more agents
Jose L. Jimenez, Mourad Tighiouart, Mauro Gasparini
Drug combination trials are increasingly common nowadays in clinical research. However, very few methods have been developed to consider toxicity attributions in the dose escalatio…
stat.ME2017
Comparison between continuous and discrete doses using Escalation With Overdose Control
Márcio Augusto Diniz, Mourad Tighiouart, André Rogatko
Although there is an extensive statistical literature showing the disadvantages of discretizing continuous variables, categorization is a common practice in clinical research which…