1 citations · 1 across the 2 of their papers we have counts for
4 papers
Visualizing adverse events in clinical trials using correspondence analysis with R-package visae
Márcio A. Diniz, Gillian Gresham, Sungjin Kim +6
We propose to apply stacked CA using contribution biplots as a tool to explore differences in AE data among treatments in clinical trials. We defined five levels of refinement for…
A Nonparametric Bayesian Design for Drug Combination Cancer Trials
Zahra S. Razaee, Galen Wien-Cook, Mourad Tighiouart
We propose an adaptive design for early phase drug combination cancer trials with the goal of estimating the maximum tolerated dose (MTD). A nonparametric Bayesian model, using bet…
A Bayesian seamless phase I-II trial design with two stages for cancer clinical trials with drug combinations
José L. Jiménez, Sungjin Kim, Mourad Tighiouart
The use of drug combinations in clinical trials is increasingly common during the last years since a more favorable therapeutic response may be obtained by combining drugs. In phas…
Comparison between continuous and discrete doses using Escalation With Overdose Control
Márcio Augusto Diniz, Mourad Tighiouart, André Rogatko
Although there is an extensive statistical literature showing the disadvantages of discretizing continuous variables, categorization is a common practice in clinical research which…