96 citations · 118 across the 6 of their papers we have counts for
3 papers · 1 filter
Degradation rate uniformity determines success of oscillations in repressive feedback regulatory networks
Karen M. Page, Ruben Perez-Carrasco
Ring oscillators are biochemical circuits consisting of a ring of interactions capable of sustained oscillations. The non-linear interactions between genes hinder the analytical in…
The power of the AC-DC circuit: Operating principles of a simple multi-functional transcriptional network motif
Ruben Perez-Carrasco, Chris P. Barnes, Yolanda Schaerli +3
Genetically encoded regulatory circuits control biological function. A major focus of systems biology is to understand these circuits by establishing the relationship between speci…
Intrinsic noise profoundly alters the dynamics and steady state of morphogen-controlled bistable genetic switches
Ruben Perez-Carrasco, Pilar Guerrero, James Briscoe +1
During tissue development, patterns of gene expression determine the spatial arrangement of cell types. In many cases, gradients of secreted signaling molecules - morphogens - guid…