Elastic Correlations in Nucleosomal DNA Structure
arXiv:q-bio/0701014 · doi:10.1103/PhysRevLett.94.238102
Abstract
The structure of DNA in the nucleosome core particle is studied using an elastic model that incorporates anisotropy in the bending energetics and twist-bend coupling. Using the experimentally determined structure of nucleosomal DNA [T.J. Richmond and C.A. Davey, Nature {\bf 423}, 145 (2003)], it is shown that elastic correlations exist between twist, roll, tilt, and stretching of DNA, as well as the distance between phosphate groups. The twist-bend coupling term is shown to be able to capture these correlations to a large extent, and a fit to the experimental data yields a new estimate of G=25 nm for the value of the twist-bend coupling constant.
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Cited by in corpus (8)
- Twist-bend coupling and the torsional response of double-stranded DNA
- Bend-Induced Twist Waves and the Structure of Nucleosomal DNA
- DNA elasticity from coarse-grained simulations: the effect of groove asymmetry
- Twist-bend coupling and the statistical mechanics of the twistable worm-like chain model of DNA: perturbation theory and beyond
- Overtwisting induces polygonal shapes in bent DNA
- Effect of Bending Anisotropy on the 3D Conformation of Short DNA Loops
- Coarse-graining DNA: Symmetry, non-local elasticity and persistence length
- Elastic Model for Dinucleosome Structure and Energy