Oscillations in molecular motor assemblies

Abstract

Autonomous oscillations in biological systems may have a biochemical origin or result from an interplay between force-generating and visco-elastic elements. In molecular motor assemblies the force-generating elements are molecular engines and the visco-elastic elements are stiff cytoskeletal polymers. The physical mechanism leading to oscillations depends on the particular architecture of the assembly. Existing models can be grouped into two distinct categories: systems with a delayed force activation and anomalous force-velocity relations. We discuss these systems within phase plane analysis known from the theory of dynamic systems and by adopting methods from control theory, the Nyquist stability criterion.

Submitted to Journal of Physics Condensed Matter (special issue "Molecular Motors")

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Cited by in corpus (9)

• Self-assembly of Active Colloidal Molecules with Dynamic Function
• Muscle as a meta-material operating near a critical point
• Physics of muscle contraction
• Stochastic dynamics of small ensembles of non-processive molecular motors: the parallel cluster model
• Entropons as collective excitations in active solids
• Collective effects in intra-cellular molecular motor transport: coordination, cooperation and competetion
• Spontaneous sarcomere dynamics
• Self-organized system-size oscillation of a stochastic lattice-gas model
• Motor-driven Dynamics of Cytoskeletal FIlaments in Motility Assays