Simple models of proteins with repulsive non-native contacts

Abstract

The Go model is extended to the case when the non-native contact energies may be either attractive or repulsive. The folding temperature is found to increase with the energy of non-native contacts. The repulsive non-native contact energies may lead to folding at T=0 for some two-dimensional sequences and to reduction in complexity of disconnectivity graphs for local energy minima.

arXiv comment6 pages, latex, 9 figures, submitted to Phys. Rev. E

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