paper

Characterization and Control of the Run-and-Tumble Dynamics of {\it Escherichia Coli}

arXiv:2212.11222 · doi:10.1103/PhysRevLett.132.038302

Abstract

We characterize the full spatiotemporal gait of populations of swimming {\it Escherichia coli} using renewal processes to analyze the measurements of intermediate scattering functions. This allows us to demonstrate quantitatively how the persistence length of an engineered strain can be controlled by a chemical inducer and to report a controlled transition from perpetual tumbling to smooth swimming. For wild-type {\it E.~coli}, we measure simultaneously the microscopic motility parameters and the large-scale effective diffusivity, hence quantitatively bridging for the first time small-scale directed swimming and macroscopic diffusion.

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