A method for virtual optical sectioning and tomography utilizing shallow depth of field

Abstract

A method is proposed for high-resolution, three-dimensional reconstruction of internal structure of objects from planar transmission images. The described approach can be used with any form of radiation or matter waves, in principle, provided that the depth of field is smaller than the thickness of the sample. The physical optics basis for the method is elucidated and the reconstruction algorithm is presented in detail. A simulated example demonstrates an application of the method to three-dimensional electron transmission imaging of a nanoparticle under realistic radiation dose and spatial resolution constraints. It is envisaged that the method can be applicable in high-resolution transmission electron microscopy, soft X-ray microscopy, ultrasound imaging and other areas.

arXiv comment20 pages, 5 figures

References in corpus (3)

• Structure retrieval at atomic resolution in the presence of multiple scattering of the electron probe
• A new solution to the curved Ewald sphere problem for 3D image reconstruction in electron microscopy
• Relative roles of multiple scattering and Fresnel diffraction in the imaging of small molecules using electrons, Part II: Differential Holographic Tomography

Cited by in corpus (1)

• Fast unified reconstruction algorithm for conventional, phase-contrast and diffraction tomography