High-precision Quantum Transmitometry of DNA and Methylene-Blue using a Frequency-Entangled Twin-Photon Beam in Type-I SPDC

Abstract

Using the coincidence-count (CC) measurement of the generated frequency-entangled twin-photons beam (TWB) via the process of type-I spontaneous parametric-down conversion (SPDC) in BBO nonlinear crystal (NLC), we have precisely measured the transmittance of very diluted Rabbit- and Human-DNA, Methylene-Blue (MB), as a disinfectant, and thin-film multilayer at near IR wavelength 810nm with an accuracy in order of $\%0.01$ due to the quantum correlation, while accuracy of classical-like measurement, single-count (SC), is in order of $\%0.1$ in our setup. Moreover, using quantum measurement of the transmittance, the different types of DNA with the same concentration, and also very diluted (in order of pg/$\mu$l) different concentrations of DNA and MB solutions are distinguished and detected with high-reliability. Interestingly, in case of Human-DNA samples in contrast to our classical-like measurement we could precisely detect and distinguish two very diluted concentrations $0.01ng/\mu \mathrm{l}$ and $0.1ng/\mu \mathrm{l}$ with high reliability while commercial standard spectrometer device of our DNA-manufacturer never could detect and distinguish them. Surprisingly, measurement on the thin-film multilayer illustrates that the introduced method in this work might be performed to cancer/brain tissues or Stem cells for cancer therapy, and may hopefully open a pave and platform for non-invasive quantum diagnosis in future.

arXiv commentThis is the first quantum optical experiment in IRAN in the context of quantum sensing and measurement and in the field of quantum biology and quantum diagnosis ; 21 pages; 4 figures; 3 tables

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• Direct generation of two-pair frequency entanglement via dual periodic poling in lithium niobate waveguides
• Analytical performance evaluation of quantum radar architectures: From single-photon to entangled-noise radars