Dynamic full-field optical coherence tomography: 3D live-imaging of retinal organoids
arXiv:1912.04052 · doi:10.1038/s41377-020-00375-8
Abstract
Optical coherence tomography offers astounding opportunities to image the complex structure of living tissue, but lacks functional information. We present dynamic full-field optical coherence tomography to image living human induced pluripotent stem cell-derived retinal organoids non-invasively. Colored images with an endogenous contrast linked to organelle motility are generated, with sub-micrometer spatial resolution and millisecond temporal resolution, opening an avenue to identify specific cell types in living tissue via their function.
arXiv comment14 pages, 5 figures, 1 table, 6 videos
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