Hamiltonian dynamics of the SIS epidemic model with stochastic fluctuations
arXiv:1902.10786 · doi:10.1038/s41598-019-52351-x
Abstract
Empirical records of epidemics reveal that fluctuations are important factors for the spread and prevalence of infectious diseases. The exact manner in which fluctuations affect spreading dynamics remains poorly known. Recent analytical and numerical studies have demonstrated that improved differential equations for mean and variance of infected individuals reproduce certain regimes of the SIS epidemic model. Here, we show they form a dynamical system that follows Hamilton's equations, which allow us to understand the role of fluctuations and their effects on epidemics. Our findings show the Hamiltonian is a constant of motion for large population sizes. For small populations, finite size effects break the temporal symmetry and induce a power-law decay of the Hamiltonian near the outbreak onset, with a parameter-free exponent. Away from onset, the Hamiltonian decays exponentially according to a constant relaxation time, which we propose as a indicator of the strength of the epidemic when fluctuations cannot be neglected.
References in corpus (14)
- The structure and function of complex networks
- Epidemic spreading in scale-free networks
- Epidemic processes in complex networks
- Weak pairwise correlations imply strongly correlated network states in a neural population
- Scale-free brain functional networks
- Effect of the Interconnected Network Structure on the Epidemic Threshold
- Disease extinction in the presence of non-Gaussian noise
- Extinction of an infectious disease: a large fluctuation in a non-equilibrium system
- Epidemic extinction and control in heterogeneous networks
- Noise induced stabilization in population dynamics
- Epidemic Extinction Paths in Complex Networks
- Fast computation method for comprehensive agent-level epidemic dissemination in networks
- Phase diagram and spectral properties of a new exactly integrable spin one quantum chain
- A Law of Nature?
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