Linker-mediated phase behavior of DNA-coated colloids
arXiv:1902.08883 · doi:10.1103/PhysRevX.9.041054
Abstract
The possibility of prescribing local interactions between nano- and microscopic components that direct them to assemble in a predictable fashion is a central goal of nanotechnology research. In this article we advance a new paradigm in which self-assembly of DNA-functionalized colloidal particles is programmed using linker oligonucleotides dispersed in solution. We find a phase diagram that is surprisingly rich compared to phase diagrams typical of other DNA-functionalized colloidal particles that interact by direct hybridization, including a re-entrant melting transition upon increasing linker concentration, and show that multiple linker species can be combined together to prescribe many interactions simultaneously. A new theory predicts the observed phase behavior quantitatively without any fitting parameters. Taken together, these experiments and model lay the groundwork for future research in programmable self-assembly, enabling the possibility of programming the hundreds of specific interactions needed to assemble fully-addressable, mesoscopic structures, while also expanding our fundamental understanding of the unique phase behavior possible in colloidal suspensions.
arXiv comment10 pages, 6 figures, supporting information
References in corpus (7)
- Reentrant Condensation of DNA induced by Multivalent Counterions
- A general theory of DNA-mediated and other valence-limited interactions
- DNA-Programmed Mesoscopic Architecture
- Phase Behavior and Selectivity of DNA-linked Nanoparticle Assemblies
- Controlling the temperature sensitivity of DNA-mediated colloidal interactions through competing linkages
- Gas-solid coexistence of adhesive spheres
- Free energy of ligand-receptor systems forming multimeric complexes
Cited by in corpus (6)
- Percolation in binary mixtures of linkers and particles: chaining {\it {vs}} branching
- Dynamics of equilibrium linked colloidal gels
- Designing superselectivity in linker-mediated multivalent nanoparticle adsorption
- Competition between self-assembly and phase separation governs high-temperature condensation of a DNA liquid
- A simple method to reprogram the binding specificity of DNA-coated colloids that crystallize
- Designed self-assembly of programmable colloidal atom-electron equivalents