A fluctuation theorem for time-series of signal-response models with the backward transfer entropy

Abstract

The irreversibility of trajectories in stochastic dynamical systems is linked to the structure of their causal representation in terms of Bayesian networks. We consider stochastic maps resulting from a time discretization with interval τof signal-response models, and we find an integral fluctuation theorem that sets the backward transfer entropy as a lower bound to the conditional entropy production. We apply this to a linear signal-response model providing analytical solutions, and to a nonlinear model of receptor-ligand systems. We show that the observational time τhas to be fine-tuned for an efficient detection of the irreversibility in time-series.

13 pages, 7 figures