Invariant death

Abstract

In nematodes, environmental or physiological perturbations alter death's scaling of time. In human cancer, genetic perturbations alter death's curvature of time. Those changes in scale and curvature follow the constraining contours of death's invariant geometry. I show that the constraints arise from a fundamental extension to the theories of randomness, invariance and scale. A generalized Gompertz law follows. The constraints imposed by the invariant Gompertz geometry explain the tendency of perturbations to stretch or bend death's scaling of time. Variability in death rate arises from a combination of constraining universal laws and particular biological processes.

F1000Research 5:2076

References in corpus (6)

• The common patterns of nature
• Generative models versus underlying symmetries to explain biological pattern
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• Measurement Invariance, Entropy, and Probability
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• d'Alembert's direct and inertial forces acting on populations: the Price equation and the fundamental theorem of natural selection

Cited by in corpus (1)

• The Price equation program: simple invariances unify population dynamics, thermodynamics, probability, information and inference