Pfcrmp May Play a Key Role in Chloroquine Antimalarial Action and Resistance Development

Abstract

It was proposed earlier that Pfcrmp (Plasmodium falciparum chloroquine resistance marker protein) may be the chloroquine's target protein in nucleus. In this communication, further evidence is presented to support the view that Pfcrmp may play a key role in chloroquine antimalarial actions as well as resistance development.

5 pages, 1 figure, 2 tables

Cited by in corpus (2)

• Cell-Cycle-Associated Amplified Genomic-DNA Fragments (CAGFs) Might Be Involved in Chloroquine Action and Resistance in Plasmodium falciparum
• Certain amplified genomic-DNA fragments (AGFs) may be involved in cell cycle progression and chloroquine is found to induce the production of cell-cycle-associated AGFs (CAGFs) in Plasmodium falciparum