Collective dynamics of an inhomogeneous two-channel exclusion process: Theory and Monte Carlo simulations

Abstract

This work is devoted to the development of a novel theoretical approach, named hybrid approach, to handle a localized bottleneck in a symmetrically coupled two-channel totally asymmetric simple exclusion process with Langmuir kinetics. The hybrid approach is combined with singular perturbation technique to get steady-state phase diagrams and density profiles. We have thoroughly examined the role played by the strength of bottleneck, binding constant and lane-changing rate in the system dynamics. The appearances of bottleneck-induced shock, a bottleneck phase and Meissner phase are explained. Further, the critical values of bottleneck rate are identified, which signify the changes in the topology of phase diagram. It is also found that increase in lane-changing rate as well as unequal attachment, detachment rates weaken the bottleneck effect. Our theoretical arguments are in good agreement with extensively performed Monte Carlo simulations.

38 pages, 9 figures

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Cited by in corpus (2)

• Interference of two co-directional exclusion processes in the presence of a static bottleneck: a biologically motivated model
• A Biologically Motivated Asymmetric Exclusion Process: interplay of congestion in RNA polymerase traffic and slippage of nascent transcript