A nitrogen-vacancy spin based molecular structure microscope using multiplexed projection reconstruction
arXiv:1505.02904
Abstract
Methods and techniques to measure and image beyond the state-of-the-art have always been influential in propelling basic science and technology. Because current technologies are venturing into nanoscopic and molecular-scale fabrication, atomic-scale measurement techniques are inevitable. One such emerging sensing method uses the spins associated with nitrogen-vacancy (NV) defects in diamond. The uniqueness of this NV sensor is its atomic size and ability to perform precision sensing under ambient conditions conveniently using light and microwaves (MW). These advantages have unique applications in nanoscale sensing and imaging of magnetic fields from nuclear spins in single biomolecules. During the last few years, several encouraging results have emerged towards the realization of an NV spin-based molecular structure microscope. Here, we present a projection-reconstruction method that retrieves the three-dimensional structure of a single molecule from the nuclear spin noise signatures. We validate this method using numerical simulations and reconstruct the structure of a molecular phantom \b{eta}-cyclodextrin, revealing the characteristic toroidal shape.
References in corpus (20)
- High-sensitivity diamond magnetometer with nanoscale resolution
- A Diamond Nanowire Single Photon Antenna
- A robust, scanning quantum system for nanoscale sensing and imaging
- How to Enhance Dephasing Time in Superconducting Qubits
- Nanoscale NMR Spectroscopy and Imaging of Multiple Nuclear Species
- Sub-nanometer resolution in three-dimensional magnetic-resonance imaging of individual dark spins
- Sensing remote nuclear spins
- Detecting and polarizing nuclear spins with double resonance on a single electron spin
- Spin Properties of Very Shallow Nitrogen Vacancy Defects in Diamond
- Nuclear spin pair coherence in diamond for atomic scale magnetometry
- High-Resolution Correlation Spectroscopy of 13C Spins Near a Nitrogen-Vacancy Center in Diamond
- Stray-field imaging of magnetic vortices with a single diamond spin
- Proton magnetic resonance imaging with a nitrogen-vacancy spin sensor
- Scanning probe microscopy with chemical contrast by nanoscale nuclear magnetic resonance
- Radio-frequency magnetometry using a single electron spin
- Off-Resonant Manipulation of Spins in Diamond via Precessing Magnetization of a Proximal Ferromagnet
- Strong driving of a single spin using arbitrarily polarized fields
- High-dynamic-range imaging of nanoscale magnetic fields using optimal control of a single qubit
- Sub-optical resolution of single spins using magnetic resonance imaging at room temperature in diamond
- High-efficiency resonant amplification of weak magnetic fields for single spin magnetometry