Lift and down-gradient shear-induced diffusion in Red Blood Cell suspensions

Abstract

The distribution of Red Blood Cells in a confined channel flow is inhomogeneous and shows a marked depletion near the walls due to a competition between migration away from the walls and shear-induced diffusion resulting from interactions between particles. We investigated the lift of RBCs in a shear flow near a wall and measured a significant lift velocity despite the tumbling motion of cells. We also provide values for the collective and anisotropic shear-induced diffusion of a cloud of RBCs, both in the direction of shear and in the direction of vorticity. A generic down-gradient subdiffusion characterized by an exponent 1/3 is highlighted.

To appear in Phys. Rev. Lett

References in corpus (4)

• Swinging of red blood cells under shear flow
• Mechanism of margination in confined flows of blood and other multicomponent suspensions
• Hydrodynamic lift of vesicles under shear flow in microgravity
• The lift on a tank-treading ellipsoidal cell in a bounded shear flow

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