Mechanism of margination in confined flows of blood and other multicomponent suspensions
arXiv:1208.0943 · doi:10.1103/PhysRevLett.109.108102
Abstract
Flowing blood displays a phenomenon called margination, in which leukocytes and platelets are preferentially found near blood vessel walls, while erythrocytes are depleted from these regions. Here margination is investigated using direct hydrodynamic simulations of a binary suspension of stiff (s) and floppy (f) capsules, as well as a stochastic model that incorporates the key particle transport mechanisms in suspensions -- wall-induced hydrodynamic migration and shear-induced pair collisions. The stochastic model allows the relative importance of these two mechanisms to be directly evaluated and thereby indicates that margination, at least in the dilute case, is largely due to the differential dynamics of homogeneous (e.g. s-s) and heterogeneous (s-f) collisions
arXiv comment5 Pages, 4 figures
References in corpus (4)
- Deterministic and stochastic behaviour of non-Brownian spheres in sheared suspensions
- Segregation by membrane rigidity in flowing binary suspensions of elastic capsules
- Accelerated boundary integral method for multiphase flow in non-periodic geometries
- Layering instability in a confined suspension flow
Cited by in corpus (18)
- Lift and down-gradient shear-induced diffusion in Red Blood Cell suspensions
- Fluid Vesicles in Flow
- Chirality-induced bacterial rheotaxis in bulk shear flows
- Elastohydrodynamic lift at a soft wall
- Effect of tube diameter and capillary number on platelet margination and near-wall dynamics
- A microfluidic device to sort capsules by deformability: A numerical study
- Clustering of microscopic particles in constricted blood flow
- Lift at low Reynolds number
- Anti-margination of microparticles and platelets in the vicinity of branching vessels
- Margination regimes and drainage transition in confined multicomponent suspensions
- Nanoparticle diffusion in sheared cellular blood flow
- Flow-induced segregation and dynamics of red blood cells in sickle cell disease
- Pairwise hydrodynamic interactions and diffusion in a vesicle suspension
- Sorting of particles suspended in whole blood
- Fluctuations and diffusion in sheared athermal suspensions of deformable particles
- Cross-stream migration of a Brownian droplet in a polymer solution under Poiseuille flow
- Immersed boundary simulations of cell-cell interactions in whole blood
- Inhomogeneous Diffusion in Confined Colloidal Suspensions