DNA translocation through nanopores with salt gradients: The role of osmotic flow

Abstract

Recent experiments of translocation of double stranded DNA through nanopores [M. Wanunu \textit{et al.} Nature Nanotech. {\bf 5}, 160 (2010)] reveal that the DNA capture rate can be significantly influenced by a salt gradient across the pore. We show that osmotic flow combined with electrophoretic effects can quantitatively explain the experimental data on the salt-gradient dependence of the capture rate.

4 pages, 2 figures, 2 pages of supplementary online material with 2 figures, extra material added, to appear in Phys. Rev. Lett

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