CO-phylum: An Assembly-Free Phylogenomic Approach for Close Related Organisms
arXiv:1009.4141 · doi:10.1093/nar/gkt003
Abstract
Phylogenomic approaches developed thus far are either too time-consuming or lack a solid evolutionary basis. Moreover, no phylogenomic approach is capable of constructing a tree directly from unassembled raw sequencing data. A new phylogenomic method, CO-phylum, is developed to alleviate these flaws. CO-phylum can generate a high-resolution and highly accurate tree using complete genome or unassembled sequencing data of close related organisms, in addition, CO-phylum distance is almost linear with p-distance.
21 pages, 6 figures
Cited by in corpus (7)
- Cnidaria: fast, reference-free clustering of raw and assembled genome and transcriptome NGS data
- Alignment-free Genomic Analysis via a Big Data Spark Platform
- Alignment-free comparison of next-generation sequencing data using compression-based distance measures
- Whole Genome Phylogenetic Tree Reconstruction Using Colored de Bruijn Graphs
- Alignment-Free Sequence Analysis and Applications
- Anchor points for genome alignment based on Filtered Spaced Word Matches
- Inference of Markovian Properties of Molecular Sequences from NGS Data and Applications to Comparative Genomics