Enhanced stochastic oscillations in autocatalytic reactions

Abstract

We study a simplified scheme of $k$ coupled autocatalytic reactions, previously introduced by Togashi and Kaneko. The role of stochastic fluctuations is elucidated through the use of the van Kampen system-size expansion and the results compared with direct stochastic simulations. Regular temporal oscillations are predicted to occur for the concentration of the various chemical constituents, with an enhanced amplitude resulting from a resonance which is induced by the intrinsic graininess of the system. The associated power spectra are determined and have a different form depending on the number of chemical constituents, $k$. We make detailed comparisons in the two cases $k=4$ and $k=8$. Agreement between the theoretical and numerical results for the power spectrum are good in both cases. The resulting spectrum is especially interesting in the $k=8$ system, since it has two peaks, which the system-size expansion is still able to reproduce accurately.

Submitted to Phys. Rev. E

References in corpus (1)

• Amplified biochemical oscillations in cellular systems

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