Funnels in Energy Landscapes

Abstract

Local minima and the saddle points separating them in the energy landscape are known to dominate the dynamics of biopolymer folding. Here we introduce a notion of a "folding funnel" that is concisely defined in terms of energy minima and saddle points, while at the same time conforming to a notion of a "folding funnel" as it is discussed in the protein folding literature.

6 pages, 3 figures, submitted to European Conference on Complex Systems 2007

References in corpus (2)

• Evolution of the Potential Energy Surface with Size for Lennard-Jones Clusters
• Energy landscapes, supergraphs, and "folding funnels" in spin systems

Cited by in corpus (4)

• Efficient exploration of discrete energy landscapes
• Changes of graph structure of transition probability matrices indicate the slowest kinetic relaxations
• Slowest kinetic modes revealed by metabasin renormalization
• Mean first passage times reconstruct the slowest relaxations in potential energy landscapes of nanoclusters