Effects of crosslinks on motor-mediated filament organization

Abstract

Crosslinks and molecular motors play an important role in the organization of cytoskeletal filament networks. Here we incorporate the effect of crosslinks into our model of polar motor-filament organization [Phys. Rev. E {\bf 71}, 050901 (2005)], through suppressing the relative sliding of filaments in the course of motor-mediated alignment. We show that this modification leads to a nontrivial macroscopic behavior, namely the oriented state exhibits a transverse instability in contrast to the isotropic instability that occurs without crosslinks. This transverse instability leads to the formation of dense extended bundles of oriented filaments, similar to recently observed structures in actomyosin. This model also can be applied to situations with two oppositely directed motor species or motors with different processing speeds.

15 pages, 5 figures, submitted to New. J. Phys

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Cited by in corpus (5)

• Large-scale chaos and fluctuations in active nematics
• Continuous theory of active matter systems with metric-free interactions
• Microscopic basis for pattern formation and anomalous transport in two-dimensional active gels
• Kinetic theory of pattern formation in mixtures of microtubules and molecular motors
• Supramolecular assemblies in active motor-filament systems: micelles, bilayers, and foams