226 citations
- Feinstein Institute for Medical ResearchUS26 papers
- University of Science and Technology of ChinaCN6 papers
- Hofstra UniversityUS4 papers
- Universidad Nacional Autónoma de MéxicoMX4 papers
- National Centre of Scientific Research "Demokritos"GR3 papers
- Zucker Hillside HospitalUS3 papers
- Columbia UniversityUS2 papers
- Stony Brook UniversityUS2 papers
- AIRI - Artificial Intelligence Research InstituteRU1 paper
- Aristotle University of ThessalonikiGR1 paper
- Athena Research and Innovation Center In Information Communication & Knowledge TechnologiesGR1 paper
- Barcelona Supercomputing CenterES1 paper
8 papers · 1 filter
A Pathologist-Annotated Dataset for Validating Artificial Intelligence: A Project Description and Pilot Study
Sarah N Dudgeon, Si Wen, Matthew G Hanna +19
Purpose: In this work, we present a collaboration to create a validation dataset of pathologist annotations for algorithms that process whole slide images (WSIs). We focus on data…
Using Volcano Plots and Regularized-Chi Statistics in Genetic Association Studies
Wentian Li, Jan Freudenberg, Young Ju Suh +1
Labor intensive experiments are typically required to identify the causal disease variants from a list of disease associated variants in the genome. For designing such experiments,…
Application of Volcano Plots in Analyses of mRNA Differential Expressions with Microarrays
Wentian Li
Volcano plot displays unstandardized signal (e.g. log-fold-change) against noise-adjusted/standardized signal (e.g. t-statistic or -log10(p-value) from the t test). We review the b…
Fractal Characterizations of MAX Statistical Distribution in Genetic Association Studies
Wentian Li, Yaning Yang
Two non-integer parameters are defined for MAX statistics, which are maxima of simpler test statistics. The first parameter, , is the fractional number of tests, repre…
Effective Sample Size: Quick Estimation of the Effect of Related Samples in Genetic Case-Control Association Analyses
Yaning Yang, Elaine F. Remmers, Chukwuma B. Ogunwole +3
Affected relatives are essential for pedigree linkage analysis, however, they cause a violation of the independent sample assumption in case-control association studies. To avoid t…
Does Logarithm Transformation of Microarray Data Affect Ranking Order of Differentially Expressed Genes?
Wentian Li, Young Ju Suh, Jingshan Zhang
A common practice in microarray analysis is to transform the microarray raw data (light intensity) by a logarithmic transformation, and the justification for this transformation is…