428 citations
- Max Planck SocietyDE21 papers
- Harvard UniversityUS10 papers
- Peking UniversityCN5 papers
- RIKEN Center for Computational ScienceJP4 papers
- State Key Laboratory of Turbulence and Complex Systems3 papers
- University of ManchesterGB3 papers
- Centre National de la Recherche ScientifiqueFR2 papers
- Christian-Albrechts-Universität zu KielDE2 papers
- Dana-Farber Cancer InstituteUS2 papers
- InsermFR2 papers
- Institut de Biologie de l'École Normale SupérieureFR2 papers
- Leipzig UniversityDE2 papers
7 papers · 1 filter
A multi-phenotypic cancer model with cell plasticity
Da Zhou, Yue Wang, Bin Wu
The conventional cancer stem cell (CSC) theory indicates a hierarchy of CSCs and non-stem cancer cells (NSCCs), that is, CSCs can differentiate into NSCCs but not vice versa. Howev…
Cancer initiation with epistatic interactions between driver and passenger mutations
Benedikt Bauer, Reiner Siebert, Arne Traulsen
We investigate the dynamics of cancer initiation in a mathematical model with one driver mutation and several passenger mutations. Our analysis is based on a multi type branching p…
Gains from switching and evolutionary stability in multi-player matrix games
Jorge Peña, Laurent Lehmann, Georg Nöldeke
In this paper we unify, simplify, and extend previous work on the evolutionary dynamics of symmetric -player matrix games with two pure strategies. In such games, gains from swi…
Self tolerance in a minimal model of the idiotypic network
Robert Schulz, Benjamin Werner, Ulrich Behn
We consider the problem of self tolerance in the frame of a minimalistic model of the idiotypic network. A node of this network represents a population of B lymphocytes of the same…
A deterministic model for the occurrence and dynamics of multiple mutations in hierarchically organized tissues
B. Werner, D. Dingli, A. Traulsen
We model a general, hierarchically organized tissue by a multi compartment approach, allowing any number of mutations within a cell. We derive closed solutions for the deterministi…
Mutualism and evolutionary multiplayer games: revisiting the Red King
Chaitanya S. Gokhale, Arne Traulsen
Coevolution of two species is typically thought to favour the evolution of faster evolutionary rates helping a species keep ahead in the Red Queen race, where `it takes all the run…