533 citations
Counting papers with at most 25 authors, so collaboration author lists do not stand in for the people here.
- Center for Devices and Radiological HealthUS9 papers
- University of Maryland, College ParkUS9 papers
- Center for Drug Evaluation and ResearchUS6 papers
- Harvard UniversityUS6 papers
- University of ChicagoUS6 papers
- Center for Biologics Evaluation and ResearchUS5 papers
- Office of ScienceUS5 papers
- Massachusetts General HospitalUS4 papers
- New York UniversityUS4 papers
- University of California, IrvineUS4 papers
- Cornell UniversityUS3 papers
- Food and Drug AdministrationTH3 papers
8 papers · 1 filter
Influence of shear rate and surface chemistry on thrombus formation in micro-crevice
Mansur Zhussupbekov, Wei-Tao Wu, Megan A. Jamiolkowski +2
Thromboembolic complications remain a central issue in management of patients on mechanical circulatory support. Despite the best practices employed in design and manufacturing of…
Hi3+3: A Model-Assisted Dose-Finding Design Borrowing Historical Data
Yunshan Duan, Sue-Jane Wang, Yuan Ji
Background -- In phase I clinical trials, historical data may be available through multi-regional programs, reformulation of the same drug, or previous trials for a drug under the…
A Pathologist-Annotated Dataset for Validating Artificial Intelligence: A Project Description and Pilot Study
Sarah N Dudgeon, Si Wen, Matthew G Hanna +19
Purpose: In this work, we present a collaboration to create a validation dataset of pathologist annotations for algorithms that process whole slide images (WSIs). We focus on data…
Scaling up the lattice dynamics of amorphous materials by orders of magnitude
Ivan Kriuchevskyi, Vladimir V. Palyulin, Rico Milkus +3
We generalise the non-affine theory of viscoelasticity for use with large, well-sampled systems of arbitrary chemical complexity. Having in mind predictions of mechanical and vibra…
Hadamard magnetization transfers achieve dramatic sensitivity enhancements in homonuclear multidimensional NMR correlations of labile sites in proteins, polysaccharides and nucleic acids
Mihajlo Novakovic, Eriks Kupce, Andreas Oxenfarth +4
EXSY, TOCSY and NOESY lie at the foundation of homonuclear NMR experiments in organic and pharmaceutical chemistry, as well as in structural biology. Limited magnetization transfer…
The importance of transparency and reproducibility in artificial intelligence research
Benjamin Haibe-Kains, George Alexandru Adam, Ahmed Hosny +17
In their study, McKinney et al. showed the high potential of artificial intelligence for breast cancer screening. However, the lack of detailed methods and computer code undermines…
A sharp interface Lagrangian-Eulerian method for rigid-body fluid-structure interaction
Ebrahim M. Kolahdouz, Amneet P. S. Bhalla, Lawrence N. Scotten +2
This paper introduces a sharp interface method to simulate fluid-structure interaction (FSI) involving rigid bodies immersed in viscous incompressible fluids. The capabilities of t…
Considering discrepancy when calibrating a mechanistic electrophysiology model
Chon Lok Lei, Sanmitra Ghosh, Dominic G. Whittaker +14
Uncertainty quantification (UQ) is a vital step in using mathematical models and simulations to take decisions. The field of cardiac simulation has begun to explore and adopt UQ me…