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q-bio.GN2013
Change Point Analysis of Histone Modifications Reveals Epigenetic Blocks Linking to Physical Domains
Mengjie Chen, Haifan Lin, Hongyu Zhao
Histone modification is a vital epigenetic mechanism for transcriptional control in eukaryotes. High-throughput techniques have enabled whole-genome analysis of histone modificatio…
q-bio.GN2013★ 142 cited
TrAp: a Tree Approach for Fingerprinting Subclonal Tumor Composition
Francesco Strino, Fabio Parisi, Mariann Micsinai +1
Revealing the clonal composition of a single tumor is essential for identifying cell subpopulations with metastatic potential in primary tumors or with resistance to therapies in m…