output
20072024
most citedComputer Folding of RNA Tetraloops: Identification of Key Force Field Deficiencies

164 citations

11 papers

q-bio.BM2024★ 2 cited

Molecular simulations to investigate the impact of N6-methylation in RNA recognition: Improving accuracy and precision of binding free energy prediction

Valerio Piomponi, Miroslav Krepl, Jiri Sponer +1

N6-methyladenosine (m6A) is a prevalent RNA post-transcriptional modification that plays crucial roles in RNA stability, structural dynamics, and interactions with proteins. The YT…

q-bio.BM2024★ 13 cited

RNA Dynamics from Experimental and Computational Approaches

Giovanni Bussi, Massimiliano Bonomi, Paraskevi Gkeka +16

Ribonucleic acids (RNA) are unique in that they can store genetic information, replicate and perform catalysis. Importantly, RNA molecules are highly dynamic, and thus determining…

physics.chem-ph2023★ 44 cited

Condensed Matter Systems Exposed to Radiation: Multiscale Theory, Simulations, and Experiment

Andrey V. Solov'yov, Alexey V. Verkhovtsev, Nigel J. Mason +20

This paper reviews the new highly interdisciplinary research field studying the behavior of condensed matter systems exposed to radiation. The paper highlights several relevant exa…

cs.SE2023★ 4 cited

Foundational Competencies and Responsibilities of a Research Software Engineer: Current State and Suggestions for Future Directions

Florian Goth, Renato Alves, Matthias Braun +20

The term Research Software Engineer, or RSE, emerged a little over 10 years ago as a way to represent individuals working in the research community but focusing on software develop…

q-bio.BM2023★ 9 cited

Do conformational changes contribute to the surface plasmon resonance signal?

Daniel Dobrovodský, Carmelo Di Primo

Surface plasmon resonance (SPR)-based biosensors are widely used instruments for characterizing molecular interactions. In theory the SPR signal depends only on mass changes for in…

physics.chem-ph2022★ 1 cited

Automatic learning of hydrogen-bond fixes in an AMBER RNA force field

Thorben Fröhlking, Vojtěch Mlýnský, Michal Janeček +5

The capability of current force fields to reproduce RNA structural dynamics is limited. Several methods have been developed to take advantage of experimental data in order to enfor…