output
20082025
most citedpyPESTO: A modular and scalable tool for parameter estimation for dynamic models

58 citations

5 papers

q-bio.QM2025

eMZed 3: flexible and interactive development of scalable LC-MS/MS data analysis workflows in Python

Uwe Schmitt, Jethro L. Hemmann, Nicola Zamboni +2

Liquid chromatography-mass spectrometry (LC-MS/MS) data analysis requires adaptable software solutions to meet diverse analytical needs. We present eMZed 3, a modern Python framewo…

q-bio.QM2023★ 58 cited

pyPESTO: A modular and scalable tool for parameter estimation for dynamic models

Yannik Schälte, Fabian Fröhlich, Paul J. Jost +14

Mechanistic models are important tools to describe and understand biological processes. However, they typically rely on unknown parameters, the estimation of which can be challengi…

physics.ins-det2023★ 14 cited

Laboratory-Based Correlative Soft X-ray and Fluorescence Microscopy in an Integrated Setup

Julius Reinhard, Sophia Kaleta, Johann Jakob Abel +12

Correlative microscopy is a powerful technique that combines the advantages of multiple imaging modalities to achieve a comprehensive understanding of investigated samples. For exa…

physics.bio-ph2022★ 39 cited

Visualizing the ultra-structure of microorganisms using table-top extreme ultraviolet imaging

Chang Liu, Wilhelm Eschen, Lars Loetgering +10

Table-top extreme ultraviolet (EUV) microscopy offers unique opportunities for label-free investigation of biological samples. Here, we demonstrate ptychographic EUV imaging of two…

q-bio.MN2008

Constructing a Knowledge Base for Gene Regulatory Dynamics by Formal Concept Analysis Methods

Johannes Wollbold, Reinhard Guthke, Bernhard Ganter

Our aim is to build a set of rules, such that reasoning over temporal dependencies within gene regulatory networks is possible. The underlying transitions may be obtained by discre…