most citedNatural cubic splines for the analysis of Alzheimer's clinical trials

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stat.AP2022★ 37 cited

Natural cubic splines for the analysis of Alzheimer's clinical trials

M. C. Donohue, O. Langford, P. Insel +6

Mixed model repeated measures (MMRM) is the most common analysis approach used in clinical trials for Alzheimer's disease and other progressive diseases measured with continuous ou…