223 citations · 278 across the 4 of their papers we have counts for
4 papers
Alzheimer's Clinical Research Data via R Packages: the alzverse
Michael C. Donohue, Kedir Hussen, Oliver Langford +3
Sharing clinical research data is essential for advancing research in Alzheimer's disease (AD) and other therapeutic areas. However, challenges in data accessibility, standardizati…
Natural cubic splines for the analysis of Alzheimer's clinical trials
M. C. Donohue, O. Langford, P. Insel +6
Mixed model repeated measures (MMRM) is the most common analysis approach used in clinical trials for Alzheimer's disease and other progressive diseases measured with continuous ou…
The relative efficiency of time-to-progression and continuous measures of cognition in pre-symptomatic Alzheimer's
Dan Li, Samuel Iddi, Paul S. Aisen +2
Pre-symptomatic (or Preclinical) Alzheimer's Disease is defined by biomarker evidence of fibrillar amyloid beta pathology in the absence of clinical symptoms. Clinical trials in th…
Deep learning for comprehensive forecasting of Alzheimer's Disease progression
Charles K. Fisher, Aaron M. Smith, Jonathan R. Walsh +1
Most approaches to machine learning from electronic health data can only predict a single endpoint. Here, we present an alternative that uses unsupervised deep learning to simulate…