output
20132024
most citedKartezio: Evolutionary Design of Explainable Pipelines for Biomedical Image Analysis

49 citations

6 papers

q-bio.GN2024★ 5 cited

Evidence of epigenetic oncogenesis: a turning point in cancer research

Jean-Pascal Capp, Benoît Aliaga, Vera Pancaldi

In cancer research, the term epigenetics was used in the 1970s in its modern sense encompassing non-genetic events modifying the chromatin state, mainly to oppose the emerging onco…

q-bio.QM2024

Uncovering the Genetic Basis of Glioblastoma Heterogeneity through Multimodal Analysis of Whole Slide Images and RNA Sequencing Data

Ahmad Berjaoui, Louis Roussel, Eduardo Hugo Sanchez +1

Glioblastoma is a highly aggressive form of brain cancer characterized by rapid progression and poor prognosis. Despite advances in treatment, the underlying genetic mechanisms dri…

cs.CV2023★ 49 cited

Kartezio: Evolutionary Design of Explainable Pipelines for Biomedical Image Analysis

Kévin Cortacero, Brienne McKenzie, Sabina Müller +14

An unresolved issue in contemporary biomedicine is the overwhelming number and diversity of complex images that require annotation, analysis and interpretation. Recent advances in…

q-bio.BM2020★ 28 cited

Electron transport in DNA bases: An extension of the Geant4-DNA Monte Carlo toolkit

Sara A. Zein, Marie-Claude Bordage, Ziad Francis +5

The purpose of this work is to extend the Geant4-DNA Monte Carlo toolkit to include electron interactions with the four DNA bases using a set of cross sections recently implemented…

q-bio.QM2019★ 25 cited

Unveiling new disease, pathway, and gene associations via multi-scale neural networks

Thomas Gaudelet, Noel Malod-Dognin, Jon Sanchez-Valle +3

Diseases involve complex processes and modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disea…

q-bio.MN2013

Simulation of Gene Regulatory Networks

Bernard Ycart, Frédéric Pont, Jean-Jacques Fournié

This limited review is intended as an introduction to the fast growing subject of mathematical modelling of cell metabolism and its biochemical pathways, and more precisely on path…