output
20162024
most citedAttention-Based Transformers for Instance Segmentation of Cells in Microstructures

96 citations

8 papers

q-bio.PE2024★ 1 cited

Computational and Experimental Exploration of Protein Fitness Landscapes: Navigating Smooth and Rugged Terrains

Mahakaran Sandhu, John Chen, Dana Matthews +6

Proteins evolve through complex sequence spaces, with fitness landscapes serving as a conceptual framework that links sequence to function. Fitness landscapes can be smooth, where…

cs.CV2023

The TYC Dataset for Understanding Instance-Level Semantics and Motions of Cells in Microstructures

Christoph Reich, Tim Prangemeier, Heinz Koeppl

Segmenting cells and tracking their motion over time is a common task in biomedical applications. However, predicting accurate instance-wise segmentation and cell motions from micr…

cs.CV2023★ 5 cited

An Instance Segmentation Dataset of Yeast Cells in Microstructures

Christoph Reich, Tim Prangemeier, André O. Françani +1

Extracting single-cell information from microscopy data requires accurate instance-wise segmentations. Obtaining pixel-wise segmentations from microscopy imagery remains a challeng…

cond-mat.soft2023★ 5 cited

Using holographic microscopy to measure the effect of confinement on crowding agents in lipid vesicles

Yaam Deckel, Lauren A. Lowe, Siddharth Rawat +3

The hydrodynamic effects of macromolecular crowding inside cells is often studied in vitro by using polymers as crowding reagents. Confinement of polymers inside cell-sized droplet…

cond-mat.soft2022★ 2 cited

Measuring vesicle loading with holographic microscopy and bulk light scattering

Lan Hai Anh Tran, Lauren A. Lowe, Matthew Turner +5

We report efforts to quantify the loading of cell-sized lipid vesicles using in-line digital holographic microscopy. This method does not require fluorescent reporters, fluorescent…

cs.CV2020★ 96 cited

Attention-Based Transformers for Instance Segmentation of Cells in Microstructures

Tim Prangemeier, Christoph Reich, Heinz Koeppl

Detecting and segmenting object instances is a common task in biomedical applications. Examples range from detecting lesions on functional magnetic resonance images, to the detecti…

q-bio.QM2020★ 9 cited

Multiclass Yeast Segmentation in Microstructured Environments with Deep Learning

Tim Prangemeier, Christian Wildner, André O. Françani +2

Cell segmentation is a major bottleneck in extracting quantitative single-cell information from microscopy data. The challenge is exasperated in the setting of microstructured envi…

eess.SY2016★ 2 cited

Dynamic Network Reconstruction from Heterogeneous Datasets

Zuogong Yue, Johan Thunberg, Wei Pan +2

Performing multiple experiments is common when learning internal mechanisms of complex systems. These experiments can include perturbations to parameters or external disturbances.…