28 citations
3 papers
physics.flu-dyn2023★ 9 cited
In vitro evaluation of solution-based pressurised metered dose inhaler sprays with low GWP propellants
Daniel Duke, Lingzhe Rao, Benjamin Myatt +4
BACKGROUND: The impending transition from high Global Warming Potential (GWP) propellants such as HFA134a to low-GWP alternatives such as HFA152a and HFO1234ze(E) in pressurised me…
physics.flu-dyn2023★ 6 cited
Canister valve and actuator deposition in metered dose inhalers formulated with low-GWP propellants
Daniel J Duke, Lingzhe Rao, Alan Kastengren +6
A challenge in pressurised metered-dose inhaler formulation design is management of adhesion of the drug to the canister wall, valve and actuator internal components and surfaces,…
physics.flu-dyn2021★ 28 cited
In-vitro and Particle Image Velocimetry Studies of Dry Powder Inhalers
Larissa Gomes dos Reis, Vishal Chaugule, David F Fletcher +3
Inhalation drug delivery has seen a swift rise in the use of dry powder inhalers (DPIs) to treat chronic respiratory conditions. However, universal adoption of DPIs has been restra…