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4 papers · 1 filter
Fundamental Limits to Position Determination by Concentration Gradients
Filipe Tostevin, Pieter Rein ten Wolde, Martin Howard
Position determination in biological systems is often achieved through protein concentration gradients. Measuring the local concentration of such a protein with a spatially-varying…
Stochastic model for Soj relocation dynamics in Bacillus subtilis
Konstantin Doubrovinski, Martin Howard
The Bacillus subtilis Spo0J/Soj proteins, implicated in chromosome segregation and transcriptional regulation, show striking dynamics: Soj undergoes irregular relocations from pole…
Cellular organization by self-organization : mechanisms and models for Min protein dynamics
Martin Howard, Karsten Kruse
We use the oscillating Min proteins of Escherichia coli as a prototype system to illustrate the current state and potential of modeling protein dynamics in space and time. We demon…
A mechanism for polar protein localization in bacteria
Martin Howard
We investigate a mechanism for the polar localization of proteins in bacteria. We focus on the MinCD/DivIVA system regulating division site placement in the rod-shaped bacterium Ba…