output
20142023
most citedMolTrans: Molecular Interaction Transformer for Drug Target Interaction Prediction

678 citations

16 papers

astro-ph.GA2023★ 6 cited

Chemo-Dynamical Tagging in the Outskirts: The Origins of Stellar Substructures in the Magellanic Clouds

César Muñoz, Antonela Monachesi, David L. Nidever +12

We present the first detailed chemical analysis from APOGEE-2S observations of stars in six regions of recently discovered substructures in the outskirts of the Magellanic Clouds e…

cs.SI2022★ 7 cited

PopNet: Real-Time Population-Level Disease Prediction with Data Latency

Junyi Gao, Cao Xiao, Lucas M. Glass +1

Population-level disease prediction estimates the number of potential patients of particular diseases in some location at a future time based on (frequently updated) historical dis…

cs.LG2021★ 2 cited

Machine Learning Applications for Therapeutic Tasks with Genomics Data

Kexin Huang, Cao Xiao, Lucas M. Glass +3

Thanks to the increasing availability of genomics and other biomedical data, many machine learning approaches have been proposed for a wide range of therapeutic discovery and devel…

eess.IV2020★ 5 cited

FLANNEL: Focal Loss Based Neural Network Ensemble for COVID-19 Detection

Zhi Qiao, Austin Bae, Lucas M. Glass +2

To test the possibility of differentiating chest x-ray images of COVID-19 against other pneumonia and healthy patients using deep neural networks. We construct the X-ray imaging da…

cs.LG2020★ 1 cited

UNITE: Uncertainty-based Health Risk Prediction Leveraging Multi-sourced Data

Chacha Chen, Junjie Liang, Fenglong Ma +3

Successful health risk prediction demands accuracy and reliability of the model. Existing predictive models mainly depend on mining electronic health records (EHR) with advanced de…

cs.LG2020★ 193 cited

SumGNN: Multi-typed Drug Interaction Prediction via Efficient Knowledge Graph Summarization

Yue Yu, Kexin Huang, Chao Zhang +3

Thanks to the increasing availability of drug-drug interactions (DDI) datasets and large biomedical knowledge graphs (KGs), accurate detection of adverse DDI using machine learning…

cs.SI2020★ 7 cited

STAN: Spatio-Temporal Attention Network for Pandemic Prediction Using Real World Evidence

Junyi Gao, Rakshith Sharma, Cheng Qian +5

Objective: The COVID-19 pandemic has created many challenges that need immediate attention. Various epidemiological and deep learning models have been developed to predict the COVI…

cs.LG2020★ 2 cited

COMPOSE: Cross-Modal Pseudo-Siamese Network for Patient Trial Matching

Junyi Gao, Cao Xiao, Lucas M. Glass +1

Clinical trials play important roles in drug development but often suffer from expensive, inaccurate and insufficient patient recruitment. The availability of massive electronic he…

q-bio.QM2020★ 678 cited

MolTrans: Molecular Interaction Transformer for Drug Target Interaction Prediction

Kexin Huang, Cao Xiao, Lucas Glass +1

Drug target interaction (DTI) prediction is a foundational task for in silico drug discovery, which is costly and time-consuming due to the need of experimental search over large d…

q-bio.MN2020★ 6 cited

SkipGNN: Predicting Molecular Interactions with Skip-Graph Networks

Kexin Huang, Cao Xiao, Lucas Glass +2

Molecular interaction networks are powerful resources for the discovery. They are increasingly used with machine learning methods to predict biologically meaningful interactions. W…

cs.LG2020★ 508 cited

DeepPurpose: a Deep Learning Library for Drug-Target Interaction Prediction

Kexin Huang, Tianfan Fu, Lucas Glass +3

Accurate prediction of drug-target interactions (DTI) is crucial for drug discovery. Recently, deep learning (DL) models for show promising performance for DTI prediction. However,…

cs.LG2019★ 1 cited

No-regret Non-convex Online Meta-Learning

Zhenxun Zhuang, Yunlong Wang, Kezi Yu +1

The online meta-learning framework is designed for the continual lifelong learning setting. It bridges two fields: meta-learning which tries to extract prior knowledge from past ta…

cs.AI2019★ 18 cited

Pre-training of Graph Augmented Transformers for Medication Recommendation

Junyuan Shang, Tengfei Ma, Cao Xiao +1

Medication recommendation is an important healthcare application. It is commonly formulated as a temporal prediction task. Hence, most existing works only utilize longitudinal elec…

eess.SP2019★ 6 cited

MINA: Multilevel Knowledge-Guided Attention for Modeling Electrocardiography Signals

Shenda Hong, Cao Xiao, Tengfei Ma +2

Electrocardiography (ECG) signals are commonly used to diagnose various cardiac abnormalities. Recently, deep learning models showed initial success on modeling ECG data, however t…

cs.LG2018★ 1 cited

RDPD: Rich Data Helps Poor Data via Imitation

Shenda Hong, Cao Xiao, Trong Nghia Hoang +3

In many situations, we need to build and deploy separate models in related environments with different data qualities. For example, an environment with strong observation equipment…

q-fin.CP2014

Semiclassical approximation in stochastic optimal control I. Portfolio construction problem

Sakda Chaiworawitkul, Patrick S. Hagan, Andrew Lesniewski

This is the first in a series of papers in which we study an efficient approximation scheme for solving the Hamilton-Jacobi-Bellman equation for multi-dimensional problems in stoch…