output
20152025
most citedgfoRmula: An R package for estimating effects of general time-varying treatment interventions via the parametric g-formula

98 citations

13 papers

stat.ME2025★ 1 cited

Illustrating implications of misaligned causal questions and statistics in settings with competing events and interest in treatment mechanisms

Takuya Kawahara, Sean McGrath, Jessica G Young

In the presence of competing events, many investigators are interested in a direct treatment effect on the event of interest that does not capture treatment effects on competing ev…

stat.ME2025

A tutorial on conducting sample size and power calculations for detecting treatment effect heterogeneity in cluster randomized trials with linear mixed models

Mary Ryan Baumann, Monica Taljaard, Patrick J. Heagerty +4

Cluster-randomized trials (CRTs) are a well-established class of designs for evaluating community-based interventions. An essential task in planning these trials is determining the…

stat.ME2022★ 15 cited

Grace periods in comparative effectiveness studies of sustained treatments

Kerollos Nashat Wanis, Aaron L. Sarvet, Lan Wen +4

Researchers are often interested in estimating the effect of sustained use of a treatment on a health outcome. However, adherence to strict treatment protocols can be challenging f…

stat.ME2022★ 14 cited

Covariate Adjustment in Randomized Clinical Trials with Missing Covariate and Outcome Data

Chia-Rui Chang, Yue Song, Fan Li +1

When analyzing data from randomized clinical trials, covariate adjustment can be used to account for chance imbalance in baseline covariates and to increase precision of the treatm…

stat.ME2022★ 18 cited

Causal inference with recurrent and competing events

Matias Janvin, Jessica G. Young, Pål C. Ryalen +1

Many research questions concern treatment effects on outcomes that can recur several times in the same individual. For example, medical researchers are interested in treatment effe…

stat.ME2021★ 18 cited

Revisiting the g-null paradox

Sean McGrath, Jessica G. Young, Miguel A. Hernán

The parametric g-formula is an approach to estimating causal effects of sustained treatment strategies from observational data. An often cited limitation of the parametric g-formul…

econ.GN2021★ 1 cited

Amnesty Policy and Elite Persistence in the Postbellum South: Evidence from a Regression Discontinuity Design

Jason Poulos

This paper investigates the impact of Reconstruction-era amnesty policy on the officeholding and wealth of elites in the postbellum South. Amnesty policy restricted the political a…

cs.LG2020★ 2 cited

Trajectory Inspection: A Method for Iterative Clinician-Driven Design of Reinforcement Learning Studies

Christina X. Ji, Michael Oberst, Sanjat Kanjilal +1

Reinforcement learning (RL) has the potential to significantly improve clinical decision making. However, treatment policies learned via RL from observational data are sensitive to…

stat.ME2020★ 5 cited

Propensity Score Weighting for Covariate Adjustment in Randomized Clinical Trials

Shuxi Zeng, Fan Li, Rui Wang

Chance imbalance in baseline characteristics is common in randomized clinical trials. Regression adjustment such as the analysis of covariance (ANCOVA) is often used to account for…

stat.AP2019

Function-on-Function Regression for the Identification of Epigenetic Regions Exhibiting Windows of Susceptibility to Environmental Exposures

Michele Zemplenyi, Mark J. Meyer, Andres Cardenas +9

The ability to identify time periods when individuals are most susceptible to exposures, as well as the biological mechanisms through which these exposures act, is of great public…

stat.CO2019★ 98 cited

gfoRmula: An R package for estimating effects of general time-varying treatment interventions via the parametric g-formula

Victoria Lin, Sean McGrath, Zilu Zhang +4

Researchers are often interested in using longitudinal data to estimate the causal effects of hypothetical time-varying treatment interventions on the mean or risk of a future outc…

stat.AP2016★ 1 cited

Evaluating hospital infection control measures for antimicrobial-resistant pathogens using stochastic transmission models: application to Vancomycin-Resistant Enterococci in intensive care units

Yinghui Wei, Theodore Kypraios, Philip D. O'Neill +3

Nosocomial pathogens such as Methicillin-Resistant {\em Staphylococcus aureus} (MRSA) and Vancomycin-resistant {\em Enterococci} (VRE) are the cause of significant morbidity and mo…

stat.AP2015★ 11 cited

Continuous Post-Market Sequential Safety Surveillance with Minimum Events to Signal

Martin Kulldorff, Ivair R. Silva

The CDC Vaccine Safety Datalink project has pioneered the use of near real-time post-market vaccine safety surveillance for the rapid detection of adverse events. Doing weekly anal…