output
20142026
most citedA new Standard DNA damage (SDD) data format

77 citations

Showing physics.bio-phShow all

6 papers · 1 filter

physics.bio-ph2021★ 17 cited

Modeling the effect of ion-induced shock waves and DNA breakage with the reactive CHARMM force field

Ida Friis, Alexey V. Verkhovtsev, Ilia A. Solov'yov +1

Ion-induced DNA damage is an important effect underlying ion-beam cancer therapy. This paper introduces the methodology of modeling DNA damage induced by a shock wave caused by a p…

physics.bio-ph2021★ 19 cited

Lethal DNA damages caused by ion-induced shock waves in cells

Ida Friis, Alexey V. Verkhovtsev, Ilia A. Solov'yov +1

The elucidation of fundamental mechanisms underlying ion-induced radiation damage of biological systems is crucial for the advancement of radiotherapy with ion beams and for radiat…

physics.bio-ph2017★ 25 cited

The effect of ion-induced shock waves on the transport of reacting species around energetic ion tracks

Pablo de Vera, Eugene Surdutovich, Nigel J. Mason +2

The passage of energetic ions through tissue initiates a series of physico-chemical events, which lead to biodamage. The study of this scenario using a multiscale approach brought…

physics.bio-ph2017★ 25 cited

Radial doses around energetic ion tracks and the onset of shock waves on the nanoscale

Pablo de Vera, Eugene Surdutovich, Nigel J. Mason +1

Energetic ions lose their energy in tissue mainly by ionising its molecules. This produces secondary electrons which transport this energy radially away from the ion path. The rang…

physics.bio-ph2016★ 26 cited

Molecular dynamics study of accelerated ion-induced shock waves in biological media

Pablo de Vera, Nigel J. Mason, Fred. J. Currell +1

We present a molecular dynamics study of the effects of carbon- and iron-ion induced shock waves in DNA duplexes in liquid water. We use the CHARMM force field implemented within t…

physics.bio-ph2015★ 32 cited

Transport of secondary electrons and reactive species in ion tracks

Eugene Surdutovich, Andrey V. Solov'yov

The transport of reactive species brought about by ions traversing tissue-like medium is analysed analytically. Secondary electrons ejected by ions are capable of ionizing other mo…