781 citations
4 papers · 1 filter
Biased exonization of transposed elements in duplicated genes: A lesson from the TIF-IA gene
Maayan Amit, Noa Sela, Hadas Keren +5
Background: Gene duplication and exonization of intronic transposed elements are two mechanisms that enhance genomic diversity. We examined whether there is less selection against…
Is there any sense in antisense editing?
Yossef Neeman, Dvir Dahary, Erez Y. Levanon +2
A number of recent studies have hypothesized that sense-antisense RNA transcript pairs create dsRNA duplexes that undergo extensive A-to-I RNA editing. Here we studied human and mo…
Evidence for abundant transcription of non-coding regions in the Saccharomyces cerevisiae genome
Moshe Havilio, Erez Y. Levanon, Galia Lerman +2
Background: Recent studies in a growing number of organisms have yielded accumulating evidence that a significant portion of the non-coding region in the genome is transcribed. We…
Systematic identification of abundant A-to-I editing sites in the human transcriptome
Erez Y. Levanon, Eli Eisenberg, Rodrigo Yelin +10
RNA editing by members of the double-stranded RNA-specific ADAR family leads to site-specific conversion of adenosine to inosine (A-to-I) in precursor messenger RNAs. Editing by AD…