most citedSystematic identification of abundant A-to-I editing sites in the human transcriptome

781 citations · 968 across the 5 of their papers we have counts for

collaborators

5 papers

q-bio.GN2005

Gene expression analysis reveals a strong signature of an interferon induced pathway in childhood lymphoblastic leukemia as well as in breast and ovarian cancer

Uri Einav, Yuval Tabach, Gad Getz +6

On the basis of epidemiological studies, infection was suggested to play a role in the etiology of human cancer. While for some cancers such a role was indeed demonstrated, there i…

q-bio.GN2005★ 187 cited

Evolutionarily conserved human targets of adenosine to inosine RNA editing

Erez Y. Levanon, Martina Hallegger, Yaron Kinar +5

A-to-I RNA editing by ADARs is a post-transcriptional mechanism for expanding the proteomic repertoire. Genetic recoding by editing was so far observed for only a few mammalian RNA…

q-bio.GN2004

Is abundant A-to-I RNA editing primate-specific?

Eli Eisenberg, Sergey Nemzer, Yaron Kinar +3

A-To-I RNA editing is common to all eukaryotes, associated with various neurological functions. Recently, A-to-I editing was found to occur abundantly in the human transcriptome. H…

q-bio.GN2004★ 781 cited

Systematic identification of abundant A-to-I editing sites in the human transcriptome

Erez Y. Levanon, Eli Eisenberg, Rodrigo Yelin +10

RNA editing by members of the double-stranded RNA-specific ADAR family leads to site-specific conversion of adenosine to inosine (A-to-I) in precursor messenger RNAs. Editing by AD…

q-bio.QM2004

Design Principle of Gene Expression Used by Human Stem Cells; Implication for Pluripotency

Michal Golan-Mashiach, Jean-Eudes Dazard, Sharon Gerecht-Nir +12

Human embryonic stem cells (ESC) are undifferentiated and are endowed with the capacities of self renewal and pluripotential differentiation. Adult stem cells renew their own tissu…