output
20142023
most citedCombining isotonic regression and EM algorithm to predict genetic risk under monotonicity constraint

20 citations

7 papers

cs.GR2023★ 2 cited

Neural Parametric Surfaces for Shape Modeling

Lei Yang, Yongqing Liang, Xin Li +6

The recent surge of utilizing deep neural networks for geometric processing and shape modeling has opened up exciting avenues. However, there is a conspicuous lack of research effo…

stat.AP2019★ 1 cited

Bayesian Gamma-Negative Binomial Modeling of Single-Cell RNA Sequencing Data

Siamak Zamani Dadaneh, Paul de Figueiredo, Sing-Hoi Sze +2

Background: Single-cell RNA sequencing (scRNA-seq) is a powerful profiling technique at the single-cell resolution. Appropriate analysis of scRNA-seq data can characterize molecula…

q-bio.NC2019★ 5 cited

Simulating Cognition with Quantum Computers

Hongbin Wang, Jack W. Smith, Yanlong Sun

There are inherent limits in classical computation for it to serve as an adequate model of human cognition. In particular, non-commutativity, while ubiquitous in physics and psycho…

q-bio.QM2018★ 6 cited

Fisher information matrix for single molecules with stochastic trajectories

Milad R. Vahid, Bernard Hanzon, Raimund J. Ober

Tracking of objects in cellular environments has become a vital tool in molecular cell biology. A particularly important example is single molecule tracking which enables the study…

stat.AP2018★ 5 cited

Differential Expression Analysis of Dynamical Sequencing Count Data with a Gamma Markov Chain

Ehsan Hajiramezanali, Siamak Zamani Dadaneh, Paul de Figueiredo +3

Next-generation sequencing (NGS) to profile temporal changes in living systems is gaining more attention for deriving better insights into the underlying biological mechanisms comp…

cs.DS2017

Optimum Search Schemes for Approximate String Matching Using Bidirectional FM-Index

Kiavash Kianfar, Christopher Pockrandt, Bahman Torkamandi +2

Finding approximate occurrences of a pattern in a text using a full-text index is a central problem in bioinformatics and has been extensively researched. Bidirectional indices hav…

stat.AP2014★ 20 cited

Combining isotonic regression and EM algorithm to predict genetic risk under monotonicity constraint

Jing Qin, Tanya P. Garcia, Yanyuan Ma +3

In certain genetic studies, clinicians and genetic counselors are interested in estimating the cumulative risk of a disease for individuals with and without a rare deleterious muta…