35 citations
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q-bio.MN2014★ 3 cited
Ligand-dependent opening of the multiple AMPA receptor conductance states: a concerted model
Ranjita Dutta Roy, Christian Rosenmund, Stuart J Edelstein +1
Modulation of the properties of AMPA receptors at the post-synaptic membrane is one of the main suggested mechanisms behind synaptic plasticity in the central nervous system of ver…
q-bio.MN2014★ 35 cited
Modulation of calmodulin lobes by different targets: an allosteric model with hemiconcerted conformational transitions
Massimo Lai, Denis Brun, Stuart J Edelstein +1
Calmodulin, the ubiquitous calcium-activated second messenger in eukaryotes, is an extremely versatile molecule involved in many biological processes: muscular contraction, synapti…
q-bio.MN2012★ 31 cited
A Dynamical Model Reveals Gene Co-Localizations in Nucleus
Jing Kang, Bing Xu, Ye Yao +4
Co-localization of networks of genes in the nucleus is thought to play an important role in determining gene expression patterns. Based upon experimental data, we built a dynamical…