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stat.ME2025★ 1 cited
Efficient Inference in First Passage Time Models
Sicheng Liu, Alexander Fengler, Michael J. Frank +1
First passage time models describe the time it takes for a random process to exit a region of interest and are widely used across various scientific fields. Fast and accurate numer…
stat.ME2024
Joint model with latent disease age: overcoming the need for reference time
Juliette Ortholand, Nicolas Gensollen, Stanley Durrleman +1
Introduction: Heterogeneity of the progression of neurodegenerative diseases is one of the main challenges faced in developing effective therapies. With the increasing number of la…
stat.ME2019★ 1 cited
Simulation of virtual cohorts increases predictive accuracy of cognitive decline in MCI subjects
Igor Koval, Stéphanie Allassonnière, Stanley Durrleman
The ability to predict the progression of biomarkers, notably in NDD, is limited by the size of the longitudinal data sets, in terms of number of patients, number of visits per pat…